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Anti -Cytochrome C Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012190
產(chǎn)品規(guī)格:
100ul
Applications:
WB|IHC/IF
Species:
H/M/R,H/M/R
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information



Description

Cytochrome C rabbit polyclonal antibody

Protein full name

Cytochrome c

Synonyms

CYCS, CYC, HCS, THC4, cytochrome c, somatic, Cytochrome c, cyt c

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c

Isotype

IgG

Purity

Affinity purification

Subcellular location

Mitochondrion intermembrane space

Predicted MW.

12 kDa

Observed MW.

12 kDa

Uniprot ID

P99999, P62898, P62897




Applications



Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, lung

IHC/IF

Human, Mouse, Rat

1: 200-1: 2000

breast cancer, heart, kidney, lung, lung cancer




Background     


Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.




Images



Western blot analysis of Cytochrome (GB11080) at dilution of 1: 500

Immunohistochemistry of paraffin embedded human breast cancer using Cytochrome (GB11080) at dilution of 1: 2000 (300x lens)

Immunohistochemistry of paraffin embedded human lung cancer using Cytochrome (GB11080) at dilution of 1: 2000 (300x lens)

Immunohistochemistry of paraffin embedded mouse heart using Cytochrome (GB11080) at dilution of 1: 2000 (300x lens)

Immunohistochemistry of paraffin embedded mouse lung using Cytochrome (GB11080) at dilution of 1: 2000 (300x lens)

Immunohistochemistry of paraffin embedded rat kidney using Cytochrome (GB11080) at dilution of 1: 2000 (300x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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