KLH conjugated Synthetic peptide corresponding to Mouse β-catenin
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cytoplasm, Nucleus, Cell junction
Predicted MW.
92 kDa
Observed MW.
92 kDa
Uniprot ID
P35222, Q02248, Q9WU82
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 500-1: 1000
brain
IHC/IF
Human, Mouse, Rat
1: 500-1: 2000
colon, small intestine, stomach
Background
β-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to γ-catenin, also known as plakoglobin. Beta-catenin is widely expressed in many tissues. In cardiac muscle, beta-catenin localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocytes.
Images
Western blot analysis of β-catenin (GB11015) at dilution of 1: 500
Immunohistochemistry of paraffin embedded human stomach using β-catenin (GB11015) at dilution of 1: 1500 (400x lens)
Immunofluorescence of paraffin embedded human colon using β-catenin (GB11015) at dilution of 1: 500 (300x lens)
Immunofluorescence of paraffin embedded human stomach using β-catenin (GB11015) at dilution of 1: 500 (200x lens)
Immunofluorescence of paraffin embedded mouse small intestine using β-catenin (GB11015) at dilution of 1: 200 (400x lens)
Immunofluorescence of paraffin embedded rat stomach using β-catenin (GB11015) at dilution of 1: 200 (400x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .