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- Q Q：355185756
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Anti -beta Catenin Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
KT011814
產(chǎn)品規(guī)格：
100ul
Applications：
WB/IHC/IF
Species：
H/M/R,H/M/R
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
beta Catenin rabbit polyclonal antibody |
|
Protein full name |
Catenin beta-1 |
|
Synonyms |
CTNNB1, CTNNB, MRD19, armadillo, catenin beta 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse β-catenin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Nucleus, Cell junction |
|
Predicted MW. |
92 kDa |
|
Observed MW. |
92 kDa |
|
Uniprot ID |
P35222, Q02248, Q9WU82 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain |
|
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 2000 |
colon, small intestine, stomach |
Background
β-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to γ-catenin, also known as plakoglobin. Beta-catenin is widely expressed in many tissues. In cardiac muscle, beta-catenin localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocytes.
Images
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Western blot analysis of β-catenin (GB11015) at dilution of 1: 500
|
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Immunohistochemistry of paraffin embedded human stomach using β-catenin (GB11015) at dilution of 1: 1500 (400x lens)
|
|
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Immunofluorescence of paraffin embedded human colon using β-catenin (GB11015) at dilution of 1: 500 (300x lens) |
|
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Immunofluorescence of paraffin embedded human stomach using β-catenin (GB11015) at dilution of 1: 500 (200x lens) |
|
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Immunofluorescence of paraffin embedded mouse small intestine using β-catenin (GB11015) at dilution of 1: 200 (400x lens) |
|
Immunofluorescence of paraffin embedded rat stomach using β-catenin (GB11015) at dilution of 1: 200 (400x lens)
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬(wàn)物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室