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Anti -Synaptopodin Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011603
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

Synaptopodin rabbit polyclonal antibody

Protein full name

Synaptopodin

Synonyms

Synpo, Kiaa1029, SYNPO

Immunogen

Recombinant protein corresponding to Mouse Synaptopodin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

100 kDa

Observed MW.

100 kDa

Uniprot ID

Q8CC35, Q9Z327




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 800

cerebral cortex, brain, skeletal muscle, cerebellum




Background


Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.




Images


Picture 1.png

Western blot analysis of Synaptopodin (GB111379) at dilution of 1: 500


Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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