亚洲人成无码网在|国产精品无码免费专区|AV免费网站在线观看|国产丝袜精品视频一区二区|18禁黄污无遮挡无码网站|嫩模自慰一区二区三区花季|亚洲一区二区三区无码久久网站|亚洲欧美日韩中文字幕在线一区

歡迎,來到萬物生物官方網(wǎng)站!
郵箱:355185756@qq.com
全國服務熱線: 400-1016-218

Anti -NCR1 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101625
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
立即詢價 在線咨詢 400-1016-218
產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

NCR1 rabbit polyclonal

Protein full name

Natural cytotoxicity triggering receptor 1

Synonyms

Activating receptor 1, mAR-1, Lymphocyte antigen 94, Natural killer cell p46-related protein, NK-p46, NKp46, CD335, Ncr1, Ly94

Immunogen

Recombinant protein corresponding to Mouse NCR1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

37 kDa

Observed MW.

46 kDa

Uniprot ID

Q8C567, Q9Z0H5




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

spleen, thymus, lymph gland




Background


NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR) . These receptors are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. Mouse NKp46, also known as MAR-1 is a type I trans membrane protein with two extracellular Ig-like domains. It has a positive charge in its transmembrane domain that permits association with the ITAM-bearing signal adapter proteins, CD3 zeta and Fc epsilon RI gamma. Studies with neutralizing antibodies indicate that the three NCR are primarily responsible for triggering the NK-mediated lysis of many human tumor cell lines. Blocking any of the NCRs individually resulted in partial inhibition of tumor cell lysis, but nearly complete inhibition of lysis was observed if all three receptors were blocked simultaneously. NKp46 has also been implicated in recognition of virus-infected cells through its capacity to bind to viral hemagglutinins.




Images


IWestern blot analysis of NCR1 (GB111102) at dilution of 1: 1000
Lane 1: A549 cell lysate
Lane 2: RAW264.7 cell lysate
Lane 3: Jurkat cell lysate
Lane 4: Mouse spleen tissue lysate
Lane 5: Mouse thymus tissue lysate
Lane 6: Mouse lymph gland tissue lysate
Lane 7: Rat spleen tissue lysate
Lane 8: Rat thymus tissue lysate
Lane 9: Rat lymph gland tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問,請于收貨之日起七日內(nèi)向我公司總部或當?shù)剞k事處提出,并請保證該產(chǎn)品,以備本公司進行核對檢驗。如果發(fā)現(xiàn)有質(zhì)量問題,請于收貨后一月內(nèi)保留產(chǎn)品50%以上的量,以便本公司回收產(chǎn)品進行質(zhì)檢,確認產(chǎn)品質(zhì)量。如逾期,則視為已經(jīng)對本公司產(chǎn)品進行驗收。 聲明:如發(fā)生產(chǎn)品索賠事宜,本公司僅在產(chǎn)品價格范圍內(nèi)酌情賠償,恕不接受超出產(chǎn)品價格范圍之賠償。客戶在使用過程中有任何技術問題可以撥打技術售后服務電話我們隨時給予解答。

合肥萬物生物科技有限公司

客服熱線:400-1016-218

QQ:355185756

地址:安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室

服務熱線

400-1016-218

功能和特性

價格和優(yōu)惠

獲取新資料

售后服務

咨詢微信

價格咨詢
* 咨詢產(chǎn)品:
* 您的稱呼:
* 聯(lián)系方式:
* 地區(qū)城市:
* 圖片驗證:
立即詢價